Figure 1.

The risk of ovarian failure postchemotherapy is determined largely by the interaction of two factors: The type and amount of drug received and the age of the patient at treatment. Assessment of individual risk can be made using these factors; however, individual variation makes it advisable to consider fertility preservation measures even when treatment may fall into the low to moderate risk category. (Reprinted, with permission, from Meirow et al., 2010). *Vertical arrows represent the level of risk, with the greater number of arrows indicating greater risk; the horizontal arrow indicating negligible or unknown risk. **Dashed arrows represent the reduction in ovarian reserve that occurs following chemothereapy