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. 2015 Mar 28;15:88. doi: 10.1186/s12906-015-0624-5

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© Bunnoy et al.; licensee BioMed Central. 2015

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Microscopic characters of liver tissue. Liver tissue of normal rats treated with distilled water (A) and 2.0 g/kg/day of RYR extract (B), and liver tissue from hypercholesterolemic rats treated with 5.0 mg/kg/day of rosuvastatin (C), distilled water (D, G), 1.0 g/kg/day of RYR extract (E, H), and 2.0 g/kg/day of RYR extract (F, I). Original magnifications were 100x (A-F) and 200x (G-I). Lipid deposition in hepatocyte (steatosis) (arrow), steatosis with inflammatory cell infiltrations (steatosis hepatitis) (quadrilateral) and nuclear condensation (head arrow) were observed in the liver of hypercholesterolemic rats (D-I). No remarkable damage was detected in SP and SP-2 g (A, B). CV, central vein; HC, hepatic cord (H & E).