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. 2015 Mar 17;15:135. doi: 10.1186/s12885-015-1138-8

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© Gambaro et al.; licensee BioMed Central. 2015

This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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IGFBP7expression profile in normal and malignant ovarian cancer samples. A, Affymetrix U133A gene expression microarray analysis of IGFBP7 in NOSE (n = 17) and TOV samples: endometrioid (Endo) (n = 7) and serous subtypes (n = 17). B, Semi-quantitative RT-PCR analysis of IGFBP7 in NOSE and TOV samples. 18S was used as an internal control. C, IGFBP7 expression in NOSE samples (n = 11), normal whole ovary and HGSC samples (n = 79) as assayed by Ziplex Research System expression array. D, IGFBP7 expression from the Bonome dataset assessed by Affymetrix U133 Plus 2.0 in cytobrushing of OSE (n = 10) and HGSC subjected to laser microdissection (n = 53). E, Log2 tumour/normal ratios of expression values for IGFBP7 gene assessed using Custom Agilent 244 K Gene Expression Microarray in 506 HGSC samples relative to the expression values derived from adjacent normal tissue or case matched peripheral blood lymphocytes (TCGA dataset).