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CID1340132 selectively inhibits cell viability in PTEN−/− cells. Effect of CID1340132 on cell viability of (A) HCT116, (B) Hec1a, and (C) MCF10A PTEN+/+ and PTEN−/−. (D) Effect of CID1340132 on cell viability of HCT116 cells with targeted deletion of either wild-type or oncogenic PIK3CA.
