Table 1. Initial Cytotoxicity Screen.
HCT116PTEN+/+ | HCT116PTEN−/− | |||||
---|---|---|---|---|---|---|
Compounds Tested | IC50 <10 μM | % | Compounds Tested | IC50 <10 μM | % | |
Single-dose screen | 138 758 | 2052 | 1.5 | 138 758 | 1661 | 1.2 |
Ten-point dose screen | 1658 | 565 | 34.1 | 1658 | 559 | 33.7 |