Skip to main content
. 2014 Nov 6;6(1):71–84. doi: 10.18632/oncotarget.2698

Figure 2. Cisplatin and radiation resistance.

Figure 2

A. Graphs of non-viable (apoptotic+necrotic) cells measured by Annexin V/PI staining after cisplatin (after 24 hours) or radiation (after 48 hours) treatment. Orospheres are more resistant to both treatments. *P<0.05. B. Dose-response curves for IC50 calculation (UMSCC14B adherent cells, 114 (95% CI 104-126); UMSCC14B orospheres, 144 (95% CI 134-155); UMSCC103 adherent cells, 26.5 (95% CI 18-39); UMSCC103 orospheres, 58 (95% CI 47-72). C. Colony formation was measured 15 days after cisplatin or radiation treatment. Orospheres form significantly more colonies than adherent cells. *P<0.05.