Table 1. Clinicpathological characteristics and HER2 expression in EBVaGC and EBVnGC.
| Characteristic | EBVaGC N (%) | EBVnGC N (%) | †p |
|---|---|---|---|
| Gender | 0.498 | ||
| Male | 57 (84.6) | 149 (69.0) | |
| Female | 21 (15.49) | 67 (31.0) | |
| Age (years) | 0.054 | ||
| ≤40 | 17 (21.8) | 26 (12.0) | |
| 40~60 | 42 (53.8) | 114 (52.8) | |
| >60 | 19 (24.4) | 76 (35.2) | |
| Mean ± SD‡ | 52.4±13.6 | 55.1±12.0 | |
| Lauren | 0.079 | ||
| Intestinal | 18 (23.1) | 73 (33.8) | |
| Diffuse | 60 (76.9) | 143 (66.2) | |
| Clinical Stage (pTNM)|| | 0.142 | ||
| I, II | 20 (25.6) | 75 (34.7) | |
| III, IV | 58 (74.4) | 141 (65.3) | |
| Invasion | |||
| T1,T2 | 10 (12.9) | 46 (21.3) | 0.102 |
| T3,T4 | 68 (87.1) | 170 (78.7) | |
| Nodal status | |||
| N− | 20 (25.6) | 64 (29.6) | 0.504 |
| N+ | 58 (74.4) | 152 (70.4) | |
| Distant metastasis | |||
| M0 | 76 (97.4) | 199 (92.1) | 0.106 |
| M1 | 2 (2.6) | 17 (7.9) | |
| HER2 | <0.001 | ||
| 0/1+ | 74 (94.9) | 165 (76.3) | |
| 2+ | 3 (3.8) | 31 (14.4) | |
| 3+ | 1 (1.3) | 20 (9.3) | |
†
p-values were obtained from Pearson Chi-Square tests, Fisher's exact tests or Kruskal Wallis Test.
‡
SD: standard deviation.
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AJCC TNM cancer staging system.