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. 2014 Nov 16;6(1):243–257. doi: 10.18632/oncotarget.2801

Fig.4. CD147 promotes Src activation through FAK.

Fig.4

(A) Src activity in CD147-pcDNA3.1-transfected 7721 cells was blocked with Src I-1. Left panel: representative image. Right panel: quantification. (B) Src activity in 7721 or CD147-pcDNA3.1-transfected 7721 cells was blocked with FAK inhibitor (PF573,228). Left panel: representative image. Right panel: quantification. (C) Src activity in CD147-pcDNA3.1-transfected 7721 cells was blocked with FAK inhibitor-14 (Y-15). Left panel: representative image. (D) Src activity in CD147-pcDNA3.1-transfected 7721 cells was blocked with FAK siRNA (si-FAK). Left panel: representative image. Right panel: quantification. The bars represent each sample performed in triplicate, and the error bars indicate ± SD. ** P < 0.01, * P < 0.05, # P > 0.05, by one-way ANOVA.