Figure 2. β1 integrins promote BC cell migration on hOBM but have no effect on ERK/FAK cell signaling and proliferation in vitro.

A: Representative tracks showing BC cell movement on hOBM and quantification of instantaneous migrational speed and directionality. Box-plots show the medians, 75th and 25th percentiles; upper and lower whiskers indicate the 90th and 10th percentiles; circles denote outliers. B: Western blot analysis of ERK1/2 and FAK phosphorylation in BC cells cultured on TCP and hOBM. C: Cell proliferation rates on TCP and hOBM evaluated by an Alamar Blue assay. Data are represented as mean ± standard error.