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. 2014 Nov 15;6(1):332–344. doi: 10.18632/oncotarget.2788

Figure 6. Tumor development in the hTEBC is representative of clinical bone metastases from breast carcinoma patients.

Figure 6

A: Representative H&E images showing the similarity between the tumor-harboring hTEBCs and clinical specimens at the histological level. B: IHC stainings of β1 integrin expression in bone metastases from patients with ductal, lobular or mixed mammary carcinoma. β1 integrins are labelled with Alexa Fluor 488 dye (green) and nuclei counterstained with DAPI (blue). Patient case number (#), histopathological grading score (G), and hormone receptor status (ER/PR/HER2: estrogen/progesterone/human epidermal growth factor receptor) for the bone metastases are shown. BM: bone marrow, NB: new bone, B: bone, T: tumor.