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. 2015 Apr 1;5:9490. doi: 10.1038/srep09490

Figure 3. Neurological scores at 24 h after reperfusion in the mice with 20 min of global cerebral ischemia (n = 8).

Figure 3

(a, c) Western blotting analysis of GluR2 at 72 h after cell transfection and hippocampal injection of GluR2 siRNA Mm-Gria2-2. Mm-Gria2-2 remarkably reduced the expression of GluR2 protein in neuronal cells and hippocampus(*P < 0.05 vs. Sham). The upper part is the photograph of GluR2 and its corresponding β-Actin bands. (b) Analysis of the GluR2 mRNA in the neuronal cells. GluR2 siRNA remarkably decreased the mRNA of GluR2 (*P < 0.05 vs. Sham). (d) Neurological scores 24 h after reperfusion in the mice with 20 min of global cerebral ischemia. Pretreatment with EA significantly improved the neurological scores, whereas the GluR2 siRNA reversed the beneficial effect of EA pretreatment (*P < 0.05 vs. GCI; #P < 0.05 vs. EA+GCI).