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. 2015 Apr 1;5:9490. doi: 10.1038/srep09490

Figure 7. CB1R antagonists and CB1R siRNA dampened the regulatory effect of EA pretreatment on GluR2 expression (n = 5).

Figure 7

(a, b) Western blot analysis of GluR2 expression in GCI, EA+GCI, AM251+EA+GCI, SR141716A+EA+GCI and Vehicle+EA+GCI. The upper part is the photograph of GluR2 and its corresponding β-Actin bands. (*P < 0.05 vs. EA+GCI; #P < 0.05 vs. GCI). (c) Western blotting analysis of CB1R expression at 72 h after lateral ventricle injection of CB1R siRNA. CB1R siRNA remarkably reduced the expression of CB1R protein (*P < 0.05 vs. Sham). The upper part is the photograph of CB1R and its corresponding GAPDH bands. (d) Western blot analysis of GluR2 expression in GCI, EA+GCI, CB1 siRNA+EA+GCI, control siRNA+EA+GCI. There was a significant difference between EA+GCI group and CB1 siRNA+EA+GCI group. (*P < 0.05 vs. EA+GCI; #P < 0.05 vs. GCI).