. 2015 Mar 25;10:2377–2389. doi: 10.2147/IJN.S76191

Table 1.

BMD and other parameters of trabecular bone structures

Parameters	Sham	OVX	SO	EV	CIT-H	CIT-M	CIT-L	CIT-SO-H	CIT-SO-M	CIT-SO-L
BMD (mg/cm²)	282.93±9.33^b	199.79±5.23	194.88±6.06	245.65±8.19^a	227.23±2.59^b	220.85±4.53^a	212.04±5.59	240.45±3.23^b,^d	231.66±5.07^a,^c	212.34±5.66
BMC (mg)	263.84±5.25^b	147.03±6.47	148.03±5.96	246.15±10.02^b	222.08±3.39^b	204.09±7.36^b	182.172±4.39^b	233.06±4.06^b,^f	212.64±5.96^b	192.82±4.11^b,^e
TMC (mg)	245.16±4.57^b	131.83±3.33	130.49±4.29	227.08±3.17^b	201.52±3.16^b	180.23±8.08^b	163.56±6.53^b	213.25±4.29^b,^f	196.07±5.06^b,^c	182.26±6.83^b,^e
TMD (mg/cm³)	587.37±2.92^b	488.14±4.62	483.15±1.87	579.00±4.77^b	554.44±7.37^b	515.86±5.49^b	509.87±0.10^b	576.74±4.27^b,^d	535.26±4.89^b,^c	523.01±4.22^b,^g
VOB (mm³)	448.08±16.78^b	241.25±17.07	237.26±15.03	415.75±12.94^b	382.53±8.98^b	358.19±10.16^b	312.46±17.31^b	409.60±13.06^b,^d	389.99±10.59^b,^c	347.79±11.05^b,^e
CalibTbTh3D (mm)	0.76±0.04^b	0.44±0.04	0.42±0.05	0.67±0.01^b	0.61±0.02^a	0.57±0.01^a	0.50±0.01	0.64±0.01^b,^d	0.59±0.01^b,^h	0.55±0.01^a,^g
CalibTbSp3D (mm)	0.22±0.01^b	0.58±0.01	0.60±0.02	0.30±0.01^b	0.35±0.02^b	0.42±0.01^b	0.53±0.01^b	0.31±0.01^b,^d	0.36±0.02^b,^h	0.49±0.01^b,^g
BS/BV (1/mm)	2.71±0.09^a	5.44±0.11	5.49±0.14	3.41±0.05^a	3.77±0.07^a	4.06±0.08^a	4.55±0.09^a	3.68±0.06^a,^d	3.87±0.04^a,^c	4.19±0.07^a,^g
BV/TV (%)	53.62±1.10^a	38.56±1.02	38.13±1.27	50.98±1.59^a	46.11±0.84^a	44.36±1.16^a	39.20±1.22^a	49.56±0.56^a,^f	46.66±0.78^a,^c	42.95±1.04^a,^e
TbSp (mm)	0.24±0.01^a	0.69±0.03	0.70±0.02	0.32±0.01^a	0.41±0.02^a	0.45±0.01^a	0.61±0.01^a	0.34±0.01^a,^d	0.40±0.01^a,^c	0.54±0.02^a
TbTh (mm)	0.71±0.02^a	0.33±0.02	0.31±0.01	0.64±0.03^a	0.47±0.02^a	0.44±0.01^a	0.36±0.01^a	0.59±0.05^a,^d	0.48±0.01^a,^c	0.37±0.01^a
TbN (mm)	6.11±0.91^a	1.68±0.06	1.72±0.10	4.13±0.32^a	3.65±0.17^a	2.74±0.12^a	2.01±0.13^a	3.98±0.10^a,^d	3.09±0.16^a,^c	2.14±0.18^a

Notes:

P<0.05 compared to OVX;

P<0.01 compared to OVX;

P<0.05 compared to CIT-M;

P<0.05 compared to CIT-H;

P<0.05 compared to CIT-L;

P<0.01 compared to CIT-H;

P<0.01 compared to CIT-L;

P<0.01 compared to CIT-M. Data expressed as means ± standard deviation.

Abbreviations: BMD, bone mineral density; OVX, ovariectomized; SO, suet oil; EV, estradiol valerate; CIT, circinal–icaritin; H, high dosage; M, medium dosage; L, low dosage; BMC, BM content; TMC, tissue mineral content; TMD, TM density; VOB, volume of bone; CalibTbTh3D, calibration of trabecular thickness – 3-D; Sp, separation; BS/BV, bone surface over bone volume; TV, total volume; N, number.