Table 1.
Summary of literature reviewed on occult primary breast cancer.
| Median F/U (yr) | Patients | Overall survival | Recurrence-free survival | Locoregional recurrence | Distant recurrence | |||
|---|---|---|---|---|---|---|---|---|
| 5 yr OS | 10 yr OS | 5 yr RFS | 10 yr RFS | |||||
| Vlastos et al. (2001) [1] | 7.0 | BCT: 32 | 79% | 64% | 72% | 63% | 13% | 22% |
| Mast: 13 | 75% | 66% | 67% | 56% | 15% | 31% | ||
|
| ||||||||
| Galimberti et al. (2004) [2] | 3.4 | 50 | — | — | — | — | 4% | 12% |
|
| ||||||||
| Walker et al. (2010) [3] | 4.0 | BCT: 202 | 67.1% | — | — | — | — | |
| Mast: 268 | — | 63.5% | — | — | — | — | ||
| ALND: 126 | — | 58.5%* | — | — | — | — | ||
| Obs: 94 | — | 47.5%* | — | — | — | — | ||
|
| ||||||||
| He et al. (2012) [4] | 3.2 | BCT: 13 | — | — | — | — | 8% | 15% |
| Mast: 64 | — | — | — | — | 11% | 6% | ||
| ALND: 18 | — | — | — | — | 28% | 6% | ||
|
| ||||||||
| Campana et al. (1989) [5] | 9.0 | 31 | 76% | 71% | 86% | 75% | 25% | 29% |
|
| ||||||||
| Foroudi and Tiver (2000) [6] | 9.2 | BCT: 12 | — | — | — | — | 25% | 0% |
| Mast: 2 | — | — | — | — | 0% | 0% | ||
| Obs: 6 | — | — | — | — | 83% | — | ||
|
| ||||||||
| Barton et al. (2011) [7] | 5.7 | BCT: 35 | 84% | — | 64% | — | 14% | — |
| No RT: 13 (nodal and/or partial breast resection) |
85% | — | 34%* | — | 85% | — | ||
(i) *Statistically significant value.
(ii) BCT: breast conserving therapy, RT: radiotherapy, Mast: mastectomy, ALND: axillary lymph node dissection, and Obs: observation.
(iii) OS: overall survival, RFS: recurrence-free survival, F/U: follow-up period, and mo: month.
(iv) —: not reported.