Table 2.
The outcome of COH in terms of pregnancies, miscarriages, and deliveries.
| COH protocol | Statistical significance at P < 0.05 | |||
|---|---|---|---|---|
| Mild protocol | GnRH antagonist protocol (GnRH-ant) | GnRH agonist protocol (GnRH-a) | ||
| Pregnancies | 69 | 367 | 355 | |
|
| ||||
| Pregnancies (per cycle) | 41.6% | 33.5% | 32.0% |
P = 0.0414 (mild versus GnRH-ant), P = 0.0141 (mild versus GnRH-a) |
|
| ||||
| Pregnancies (per ET) | 45.7% | 36.1% | 35.3% |
P = 0.0227 (mild versus GnRH-ant), P = 0.0134 (mild versus GnRH-a) |
|
| ||||
| Miscarriages and ectopic pregnancies (per pregnancy) | 16 (23.2%) | 81 (22.1%) | 69 (19.4%) | / |
|
| ||||
| Biochemical pregnancies | 2 | 12 | 6 | / |
|
| ||||
| Live birth rate (per cycle) | 52 (31.3%) | 277 (25.3%) | 281 (25.3%) | / |
|
| ||||
| Twin deliveries | 21.2% (11/52) | 11.6% (32/277) | 18.5% (53/281) | P = 0.0163 (GnRH-ant versus GnRH-a) |
|
| ||||
| Live births after FET | 7 | 35 | 23 | / |
|
| ||||
| Cumulative live birth rate (per cycle) | 59 (35.6%) | 312 (28.5%) | 303 (27.3%) | P = 0.0275 (mild versus GnRH-a) |
|
| ||||
| Cumulative twin deliveries | 20.3% (12/59) | 13.1% (41/312) | 18.2% (55/303) | / |