Table 1. Glycolytic genes over- or under-expressed by at least a factor of 2.
| Gene | FC Pat. 2 | FC Pat. 3 | FC Pat. 4 | FC Pat. 5 | FC Pat. 6 | FC Pat. 9 | FC Pat. 10 | FC Pat. 11 | FC Pat. 12 | Average FC | p-value(from TDSIT) |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Over-expressed | |||||||||||
| ENO2 | 52.71 | 80.66 | 10.03 | 7.57 | 22.03 | 46.03 | 9.81 | 25.29 | 50.01 | 33.79 | 3.53E-06 |
| HK2 | 55.80 | 10.81 | 6.19 | 4.68 | 23.24 | 4.68 | 30.80 | 8.66 | 43.06 | 20.88 | 3.52E-05 |
| PFKP | 13.30 | 5.84 | 4.69 | 6.85 | 8.86 | 8.85 | 6.74 | 9.76 | 7.11 | 8.00 | 4.23E-08 |
| SLC2A3 | 5.89 | 6.52 | 4.55 | 5.89 | 3.10 | 11.90 | 13.48 | 3.05 | 3.37 | 6.42 | 1.30E-05 |
| ALDOC | 5.75 | 5.46 | 2.03 | 5.38 | 1.27 | 4.22 | 4.48 | 1.36 | 1.43 | 3.49 | 1.19E-03 |
| PKM | 6.06 | 2.32 | 2.41 | 2.06 | 3.18 | 3.15 | 1.22 | 3.06 | 5.23 | 3.19 | 1.72E-04 |
| PFKFB4 | 9.27 | 1.39 | 1.90 | 2.32 | 2.33 | 3.15 | 1.86 | 1.80 | 2.96 | 3.00 | 1.00E-03 |
| SLC2A1 | 2.15 | 1.49 | 1.64 | 1.29 | 1.80 | 3.99 | 1.17 | 3.72 | 3.38 | 2.29 | 1.58E-03 |
| HK1 | 2.69 | 2.33 | 1.47 | 1.45 | 2.78 | 2.58 | −1.02 | 2.68 | 3.50 | 2.27 | 5.82E-04 |
| ALDOA | 2.38 | 2.73 | 1.62 | 1.81 | 2.21 | 2.33 | 1.66 | 2.19 | 2.79 | 2.19 | 2.94E-06 |
| PGAM1 | 2.95 | 2.11 | 1.56 | 2.23 | 2.08 | 2.04 | 2.19 | 2.03 | 1.75 | 2.10 | 1.51E-06 |
| Under-expressed | |||||||||||
| ALDOB | −82.38 | −23.11 | −35.40 | −17.78 | −10.01 | −13.62 | −135.83 | −40.16 | −658.50 | −43.75 | 2.55E-05 |
| PKLR | −10.99 | A/A (1) | −12.13 | A/A | A/A | A/A | A/A | −4.63 | A/A | −8.51 | 1.13E-04 |
| PFKFB2 | −3.96 | −5.78 | −4.27 | −8.35 | −7.19 | −8.58 | −2.78 | −3.39 | −4.27 | −5.02 | 2.18E-06 |
| VHL | A/A | A/A | A/A | −3.43 | −5.45 | A/A | −3.06 | A/A | −1.44 | −3.01 | 3.96E-04 |
(1)
T/N ratio not calculated; both tumor and normal tissue calls were absent