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. 2015 Feb 17;2(2):151–186. doi: 10.18632/oncoscience.128

Table 5. Gene expression values relevant to lipid synthesis, anaplerosis, cataplerosis, and glutaminolysis.

Gene FC Pat. 2 FC Pat. 3 FC Pat. 4 FC Pat. 5 FC Pat. 6 FC Pat. 9 FC Pat. 10 FC Pat. 11 FC Pat. 12 Average FC p-value (from TDSIT)
Over-expressed
ACLY 2.15 3.23 1.62 3.07 2.44 1.97 3.13 1.87 3.54 2.56 1.05E-05
Under-expressed
ACO1 −2.98 −2.83 −2.60 −2.59 −2.99 −5.76 −1.53 −2.13 −2.88 −2.76 2.38E-05
GLS −2.81 −1.90 −3.53 −2.49 −4.43 −2.45 −1.54 −1.98 −3.71 −2.62 3.28E-05
GLS2 (1) −1.86 −3.98 −1.40 −7.23 −4.00 −2.63 −2.27 1.28 −3.18 −2.54 2.65E-03
ACACB −2.29 −2.88 −2.28 −3.10 −4.20 1.10 −1.89 −3.43 −1.79 −2.32 5.08E-04
IDH1 −2.69 −2.43 −2.21 −2.95 −3.58 −1.68 −1.22 −1.67 −2.30 −2.20 9.61E-05
GOT1 −1.09 −1.72 −3.16 −1.55 −3.59 −2.92 −1.27 −1.86 −2.75 −2.04 1.02E-03
Unchanged
ME2 1.83 1.45 1.40 1.62 1.53 1.09 1.18 1.25 2.20 1.47 7.54E-04
GOT2 −1.25 −1.18 −2.32 −1.66 −2.46 −2.28 −2.66 −1.86 −1.92 −1.89 1.76E-04
GLUD1 −1.57 −1.45 −1.02 −1.39 1.57 −4.25 −2.15 1.07 −2.89 −1.55 5.61E-02
FASN −1.22 −1.57 −1.09 −1.61 1.32 −1.28 −2.05 1.79 1.11 −1.14 3.48E-01
ME1 −1.40 −1.01 1.94 1.25 −2.32 −1.54 −1.34 2.68 −1.21 −1.03 9.00E-01
(1)

All calls were absent

HHS Vulnerability Disclosure