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Blocking Wnt5a function in SHF progenitors in the caudal SpM compromises their deployment to the OFT
| Injection solution | Embryos injected at HH14 | Embryos with DiI label at HH21 |
Embryos without DiI label at HH21 | ||
|---|---|---|---|---|---|
| In OFT (%) | In OFT + SpM (%) | In SpM (%) | |||
| DiI + Rat IgG | 16 | 10 (71%) | 2 (14.3%) | 2 (14.3%) | 2 |
| DiI + anti-Wnt5a IgG | 19 | 3 (17.6%) | 5 (29.4%) | 9 (53%) | 2 |
