Table 3.
Lentiviral Integration Profile vs. CpG Islands in Transgenic Mice
Distance to center of the CpG islands (kb) | No. of integration sites (%) | No. of ~10,000 simulated integration sites (%) | P value |
---|---|---|---|
0 ~ 5 | 4 (3.57) | 584 (5.84) | 0.37 |
5 ~ 10 | 9 (8.04) | 435 (4.35) | 0.059 |
10 ~ 25 | 11 (9.82) | 1077 (10.78) | 0.745 |
25 ~ 50 | 13(11.61) | 1169 (11.70) | 0.976 |
50 ~ 100 | 21 (18.75) | 1359 (13.60) | 0.114 |
>100 | 54 (48.32) | 5369 (53.73) | 0.245 |
Total | 112(100.00) | 9,993 (100.00) |
P value was determined by the χ2 test comparing the number of lentiviral integration sites and simulated integration sites.