TABLE 2.
Correlations between dietary PUFAs in the WHI Observational Study and Clinical Trials (n = 87,360)1
| Energy-adjusted dietary PUFAs (mg/d) |
||||||||
| EPA (20:5ω-3) | DPA (22:5ω-3) | DHA (22:6ω-3) | EPA + DPA + DHA | ALA (18:3ω-3) | LA (18:2ω-6) | AA (20:4ω-6) | LA + AA | |
| EPA (20:5ω-3) | 1.00 | |||||||
| DPA (22:5ω-3) | 0.85 | 1.00 | ||||||
| DHA (22:6ω-3) | 0.93 | 0.87 | 1.00 | |||||
| EPA + DPA + DHA | 0.97 | 0.90 | 0.99 | 1.00 | ||||
| ALA (18:3ω-3) | 0.05 | 0.01 | 0.05 | 0.05 | 1.00 | |||
| LA (18:2ω-6) | −0.05 | −0.06 | −0.05 | −0.05 | 0.11 | 1.00 | ||
| AA (20:4ω-6) | 0.42 | 0.60 | 0.49 | 0.49 | 0.73 | 0.13 | 1.00 | |
| LA + AA | −0.05 | −0.05 | −0.04 | −0.05 | 0.73 | 1.00 | 0.15 | 1.00 |
1
Spearman rank correlation coefficients of energy-adjusted dietary intakes; P-all such comparisons < 0.001. AA, arachidonic acid; ALA, α-linolenic acid; DPA, docosapentaenoic acid; LA, linoleic acid; WHI, Women’s Health Initiative.