Table 1.

Clinical characteristics of subjects

Subject	WeeFIM score a	Summary diagnosisb	Visual acuity (OD, OS)c	Shunt	Seizure	Optic nerve appearance d	Nystagmus
							Latent	Manifest
Group 1: patients with definite CVI
1	29	1,1	ND	Yes	No	Normal	No	Yes
2	37	1,1	ND	No	No	Normal	No	No
3	53	1,1	20/252, 20/320	Yes	No	ONA, C/D >0.5	Yes	No
4	23	1,1	ND	Yes	No	ONA	Yes	No
5	48	1,1	ND	No	No	Normal	No	No
6	99	1,1	20/200, 20/1280	No	No	ONA	Yes	Yes
7	58	1,1	ND	No	No	ONA, C/D >0.5	Yes	Yes
8	44	1,1	20/252, 20/400	No	No	ONA	Yes	Yes
9	20	1,1	ND	No	Yes	ONA	No	No
10	25	1,1	LP	Yes	Yes	Normal	Yes	Yes
11	64	1,1	20/640, 20/252	No	Yes	ONA, C/D >0.5	Yes	Yes
12	88	1,1	20/400, 20/200	No	No	Normal	Yes	No
13	50	1,1	ND	No	No	Normal	Yes	Yes
14	103	1,1	20/200, 20/252	No	No	Normal	Yes	Yes
15	101	1,1	20/252, 20/252	Yes	No	C/D >0.5	Yes	Yes
16	27	1,1	ND	No	No	Normal	Yes	Yes
17	29	1,1	ND	No	No	ONA	Yes	Yes
18	27	1,1	ND	No	Yes	ONA, C/D >0.5	No	No
19	18	1,1	LV	No	No	ONA, C/D >0.5	Yes	Yes
20	47	1,1	20/500, 20/640	No	No	Normal	Yes	No
21	50	1,1	ND	Yes	No	ONA, C/D >0.5	Yes	Yes
22	26	1,1	ND	No	No	ONA, C/D >0.5	Yes	Yes
23	90	1,1	ND	No	No	C/D >0.5	No	No
24	18	1,1	ND	No	No	ONA	Yes	No
25	93	1,1	ND	No	No	Normal	Yes	Yes
Group 2: patients with probable CVI vs combined anterior and posterior pathway disease
26	100	3,1	20/800, 20/400	No	No	Normal	Yes	Yes
27	32	2,2	ND	No	No	Normal	Yes	No
28	24	2,2	ND	No	Yes	Normal	Yes	Yes
29	55	2,2	ND	No	No	Normal	No	Yes
30	51	1,3	LV	No	Yes	Normal	No	No
31	38	2,2	LV	No	Yes	ONA, C/D >0.5	Yes	Yes
32	91	2,2	20/200, 20/800	No	No	ONA, C/D >0.5	Yes	Yes
33	19	2,2	LV	No	No	ONA	No	No
34	34	1,2	ND	Yes	No	Normal	No	No
35	64	1,2	ND	No	No	C/D >0.5	No	Yes
36	103	2,2	ND	Yes	Yes	ONA	No	No
37	71	4B,2	LP, 20/252	No	No	ONA	Yes	Yes
Group 3: patients with indeterminate cause of visual loss
38	123	1/5B	20/200, LP	No	No	Normal	Yes	Yes
39	111	1,1	ND	No	No	Normal	No	Yes

C/D, cup/disc ratio; CVI, cortical visual impairment; LP, light perception; LV, low vision Teller card; ND, neuro-developmental delay; OD: right eye; ONA, optic nerve atrophy; OS: left eye; WeeFIM, pediatric functional independence measure.

^aWeeFIM scores (out of maximum of 126): >95, normal; 77-95, below normal; <77, severe disability.

^bSummary diagnosis (retinal appearance for right eye, left eye):1, normal-appearing fundus; 2, straightening of temporal vessels; 3, macular ectopia, 4B, incomplete retinal detachment involving the macula 5B, total retinal detachment.

^cC/D >0.5 refers to nonglaucomatous cupping of optic nerve.

^dNeuro-developmental delay prevented visual acuity assessment.