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. Author manuscript; available in PMC: 2015 Apr 1.
Published in final edited form as: Biochim Biophys Acta. 2008 Dec 9;1793(4):726–736. doi: 10.1016/j.bbamcr.2008.11.014

Figure 4.

Figure 4

Lipid storage in liver from 20 week-old foetuses with Niemann-Pick type A (NPA) (3 cases) and type C (NPC) (3 cases) diseases. This was compared to concentrations in foetuses with lysosomal disorders not affecting the liver (controls, 5 cases). All results are expressed as mean values for each group. In NPA, the primary stored lipid, sphingomyelin, is already very elevated, and is accompanied by a prominent secondary increase of cholesterol. In NPC, massive cholesterol storage occurs, with a modest sphingomyelin increase.