Table 2: Characteristics of mothers who were beneficiaries of the public drug plan and their infants in cases of neonatal abstinence syndrome, Jan. 1, 2007 to Dec. 31, 2010 | |||||
---|---|---|---|---|---|
Characteristic | No. (%)* |
p value | |||
Opioids prescribed in the 100 d before birth n = 421 |
Opioids not prescribed in the 100 d before birth n = 197 |
||||
Infants |
|||||
Gestational age, wk, median (IQR) |
39 |
(37–40) |
38 |
(37–40) |
0.15 |
Birth weight, g, median (IQR) |
2990 |
(2685–3391) |
2947 |
(2615–3370) |
0.28 |
Male sex |
202 |
(48.0) |
97 |
(49.2) |
0.77 |
Mothers |
|||||
Age, yr, median (IQR) |
27.5 |
(24.5–31.8) |
27.8 |
(24.7–32.3) |
0.46 |
Cesarean delivery |
127 |
(30.2) |
43 |
(21.8) |
0.03 |
Neighbourhood income quintile |
|||||
Lowest |
210 |
(50.0) |
83 |
(42.1) |
0.07 |
Second lowest |
83 |
(19.7) |
50 |
(25.4) |
0.11 |
Middle |
58 |
(13.8) |
31 |
(15.7) |
0.52 |
Second highest |
38 |
(9.0) |
19 |
(9.6) |
0.80 |
Highest |
31 |
(7.4) |
12 |
(6.1) |
0.56 |
First NAS-related admission to hospital |
|||||
Birth |
396 |
(94.1) |
175 |
(88.8) |
0.02 |
Infant admission to NICU |
339 |
(80.5) |
155 |
(78.7) |
0.59 |
Length of stay, d, median (IQR) |
19 |
(9–31) |
10 |
(5–20) |
< 0.0001 |
Year following birth (infant) |
|||||
Mortality |
≤ 5† |
0 |
(0) |
NA |
|
Outpatient physician encounters, median (IQR) |
25 |
(16–38) |
17 |
(12–27) |
< 0.001 |
Admissions to hospital, no., median (IQR) |
1 |
(1–1) |
1 |
(1–1) |
0.834 |
Visits to emergency department, no., median (IQR) |
1 |
(0–2) |
0 |
(0–2) |
0.004 |
Note: IQR = interquartile range, NA = not available, NAS = neonatal abstinence syndrome, NICU = neonatal intensive care unit. *Unless otherwise indicated. †In accordance with institutional policy, the exact number is suppressed when the cell size is ≤ 5. |