Table 1: Characteristics of included studies.
Study | Sex | Mean age, yr | No. of participants* | Type of intervention for prior weight loss | Intervention type | Control | Intervention length, mo. | Location | Publication date |
---|---|---|---|---|---|---|---|---|---|
Champagne et al.17 Svetkey et al.18 |
M + F |
55 |
1032 |
Six-month diet plus group-based support |
Lifestyle (delivery strategies: Internet or personal contact) |
Self-directed |
30 |
US |
2011 |
Davidson et al.12 |
M + F |
43 |
306 |
120 mg orlistat 3×/d for 1 yr plus controlled-energy diet |
120 mg orlistat 3×/d plus weight-maintenance diet |
Placebo plus same weight-maintenance diet |
12 |
US |
1999 |
Hauptman et al.13 |
M + F |
42 |
273 |
120 mg orlistat 3×/d for 1 yr plus energy-reduced diet |
120 mg orlistat 3×/d plus weight-maintenance diet |
Placebo plus same weight-maintenance diet |
12 |
US |
2000 |
Hill et al.14 |
M + F |
46 |
369 |
Six-month hypoenergetic diet plus encouraged to exercise |
120 mg orlistat 3×/d plus dietary and behavioural counselling |
Placebo plus same diet and behavioural components |
12 |
US |
1999 |
Richelsen et al.15 |
M + F |
47 |
309 |
Eight-week very low-energy diet |
120 mg orlistat 3×/d plus energy-restricted diet and dietary and lifestyle counselling |
Placebo plus same diet and behavioural components |
36 |
Scandinavia |
2007 |
Rickel et al.19 Perri et al.20 Radcliff et al.21 |
F |
59 |
234 |
Six-month group-based lifestyle program |
Six-month group-based lifestyle program |
Newsletters with tips and recipes |
6 |
US |
2011 |
Sjöström et al.16 |
M + F |
45 |
261 |
120 mg orlistat 3×/d for 1 yr plus hypocaloric diet |
120 mg orlistat 3×/d plus weight-maintenance diet |
Placebo plus weight-maintenance diet |
12 |
Europe |
1998 |
Thomas et al.22 | Not reported | 45 | 55 | Not reported (recruited from a weight loss clinic) | Weekly emails from a dietician with dietary, behavioural and exercise advice | No contact | 6 | UK | 2011 |
Note: F = female, M = male. *If a study included multiple treatment arms with different doses of orlistat, only the 120 mg group was included.