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. 2015 Jan 13;3(1):E47–E54. doi: 10.9778/cmajo.20140050

Table 4: Effect of weight-maintenance interventions on dichotomous weight outcomes.

Outcome; intervention type Effect
Statistical heterogeneity (within-group),
p value (I2 value, %)
No. of participants No. of studies Quality of evidence rating*
RR (95% CI) Absolute risk reduction, % Number needed to treat
(95% CI)
Maintenance of loss of ≥ 5% baseline body weight
Pharmacological + behavioural
1.33 (1.15–1.54)
12.37
8 (5–18)
0.31 (14)
987
3
Moderate
Maintenance of loss of ≥ 10% baseline body weight
Pharmacological + behavioural 1.76 (0.75–4.12) 0.01 (85) 731 2 Low

Note: RR = risk ratio.
*Grading of Recommendations Assessment, Development and Evaluation (GRADE) quality of evidence rating reflects confidence in the estimate of effect assessed through 5 domains of the evidence (risk of bias, indirectness, imprecision, inconsistency and reporting bias): moderate = downgraded for risk of bias, low = downgraded for risk of bias and imprecision.