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. 2015 Apr 1;10(4):e0122410. doi: 10.1371/journal.pone.0122410

Table 1. Catalytic efficiencies (kcat/Km) of human (h) and murine (m) APC and variant APC-mediated proteolysis of the peptide substrate, S2366.

APC kcat/Km (μM-1s-1)
hWT 0.22 ±0.02
hAPC(5A) 0.20 ±0.01
hAPC(36–39) 0.22 ±0.01
hAPC(Ca-ins) 0.17 ±0.02
mWT 0.22 ±0.03
mAPC(5A) 0.21 ±0.01
mAPC(36–39) 0.23 ±0.01
mAPC(Ca-ins) 0.17 ±0.02