Table 3. Gene, promoter alleles and haplotype frequencies obtained for MBL2 polymorphism among the enrolled Zimbabwean participants.
| N | Frequency% | |
|---|---|---|
| Exon 1 allele | ||
| A normal | 587 | 80 |
| B(A>G) | 3 | 0.4 |
| C(G>A) | 141 | 20 |
| D(C>T) | 1 | 0.1 |
| Promoter alleles | ||
| -550H | 38 | 5 |
| -550L | 694 | 95 |
| -221X | 134 | 18 |
| -221Y | 598 | 82 |
| +4P | 343 | 47 |
| +4Q | 389 | 53 |
| MBL2 Exon 1 genotype | ||
| AA wild-type | 233 | 64 |
| AB (A>G) | 3 | 0.8 |
| AC(G>A) | 117 | 32 |
| AD (C>T) | 1 | 0.2 |
| CC (C>T) | 12 | 3 |
| Promoter region genotypes | ||
| -550HH | 1 | 0.3 |
| -550HL | 37 | 10.1 |
| -550LL | 328 | 89.6 |
| -221YY | 242 | 66.1 |
| -221XY | 112 | 30.0 |
| -221XX | 12 | 3.2 |
| +4PP | 74 | 20.2 |
| +4QQ | 97 | 26.5 |
| +4PQ | 195 | 53.3 |
| MBL2 Haplotypes | ||
| 1. MBL2*LYPA | 260 | 35.5 |
| 2. MBL2*LYQA | 183 | 25.0 |
| 3. MBL2*LYQC | 108 | 14.6 |
| 4. MBL2*LXPA | 58 | 7.9 |
| 5. MBL2*LXQA | 45 | 6.1 |
| 6. MBL2*HYPA | 41 | 5.6 |
| 7. MBL2*LXQC | 31 | 4.2 |
| 8. MBL2*LXPC | 2 | 0.3 |
| 9. MBL2*LYQB | 2 | 0.3 |
| 10. MBL2*HYPD | 1 | 0.1 |
| 11. MBL2*LYPB | 1 | 0.1 |
MBL2 gene and allele frequencies obtained by direct gene counting, frequencies expressed as percentages.