Table 5. Distribution of participants between MBL2 genotypes and promoter region haplotypes according to schistosoma infection status.
| MBL2 Genotype/ Haplotype | N | No infection (controls) | S. haematobium only | S. mansoni only | Coinfected with both species | P value |
|---|---|---|---|---|---|---|
| A/A | 216 | 51(24%) | 128(59%) | 15(7%) | 22(10%) | |
| A/O | 117 | 33(28%) | 62(53%) | 9(8%) | 13(11%) | |
| O/O | 11 | 4(36%) | 6(55%) | 0(0%) | 1(9%) | 0.893 |
| YAYA/YAXA | 208 | 49(23%) | 123(59%) | 14(7%) | 22(11%) | |
| XAXA/YAYO | 125 | 35(28%) | 67(54%) | 10(8%) | 13(10%) | |
| XAYO/YOYO. | 11 | 4(36%) | 6(55%) | 0(0%) | 1(9%) | 0.903 |
| Promoter region genotypes | ||||||
| -550HH | 1 | 0(0%) | 1(100%) | 0(0%) | 0(0%) | |
| -550HL | 34 | 15(44%) | 18(53%) | 0(0%) | 1(3%) | |
| -550LL | 309 | 73(24%) | 177(57%) | 24(8%) | 35(11%) | 0.051 |
| -550HY | 28 | 14(50%) | 13(46%) | 0(0%) | 1(4%) | |
| -221LY | 307 | 72(24%) | 178(58%) | 23(7%) | 34(11%) | |
| -221LX | 9 | 2(22%) | 5(56%) | 1(11%) | 1(11%) | 0.072 |
| -221YY | 228 | 65(29%) | 122(54%) | 14(6%) | 27(12%) | |
| -221XY | 106 | 21(20%) | 68(64%) | 9(8%) | 8(8%) | |
| -221XX | 10 | 2(20%) | 6(60%) | 1(10%) | 1(10%) | 0.351 |
| -550HY | 35 | 15(43%) | 19(54%) | 0(0%) | 1(3%) | |
| -221LY*LX | 309 | 73(24%) | 177(57%) | 24(8%) | 35(11%) | 0.026 |
| +4PP | 69 | 16 (23%) | 43(62%) | 3(4%) | 7(10%) | |
| +4QQ | 88 | 17(19%) | 50(57%) | 8(9%) | 13(15%) | |
| +4PQ | 187 | 55(29%) | 103(55%) | 13(7%) | 16(9%) | 0.381 |
This analysis was done using the Fisher’s exact tests, n = 344