Table 6. Distribution of participants between MBL2 genotypes and promoter region haplotypes according to schistosoma infection status.
MBL2 genotype/ haplotype | n | S. haematobium negative | S. haematobium positive | P value |
---|---|---|---|---|
A/A | 179 | 51(28%) | 128(72%) | |
A/O | 95 | 33(35%) | 62(65%) | |
O/O | 10 | 4(40%) | 6(60%) | 0.466 |
YAYA/YAXA | 172 | 49(28%) | 123(72%) | |
XAXA/YAYO | 102 | 35(34%) | 67(66%) | |
XAYO/YOYO | 10 | 4(40%) | 6(60%) | 0.505 |
Promoter genotypes | ||||
-550HH | 1 | 0(0%) | 1(100%) | |
-550HL | 33 | 15(45%) | 18(55%) | |
-550LL | 250 | 73(29%) | 177(71%) | 0.132 |
-550HY | 27 | 14(52%) | 13(48%) | |
-221LY | 250 | 72(29%) | 178(71%) | |
-221LX | 7 | 2(29%) | 5(71%) | 0.048 |
-221YY | 187 | 65(35%) | 122(65%) | |
-221XY | 89 | 21(24%) | 68(76%) | |
-221XX | 8 | 2(25%) | 6(75%) | 0.161 |
-550HY | 34 | 15(44%) | 19(56%) | |
-221LY*LX | 250 | 73(29%) | 177(71%) | 0.078 |
+4PP | 59 | 16(27%) | 43(73%) | |
+4QQ | 67 | 17(25%) | 50(75%) | |
+4PQ | 158 | 55(35%) | 103(65%) | 0.289 |
This analysis was done using the Chi Square or Fisher’s exact tests, n = 284