Table 7. Distribution of participants between MBL2 promoter region haplotypes according to HIV and S. haematobium co-infection status.
M MBL2 ggenotype/ haplotype | N | HIV-/S. haematobium- | HIV+/S. haematobium+ | HIV-/S. haematobium+ | HIV+/S. haematobium- | P value |
---|---|---|---|---|---|---|
A/A | 179 | 27(15%) | 64(36%) | 64(36%) | 24(13%) | |
A/O | 95 | 16(17%) | 30(32%) | 32(34%) | 17(18%) | |
O/O | 10 | 1(10%) | 3(30%) | 3(30%) | 330(%) | 0.802 |
YAYA/YAXA | 172 | 26(15%) | 61(36%) | 62(36%) | 23(13%) | |
XAXA/YAYO | 102 | 17(17%) | 33(32%) | 34(33%) | 18(18%) | |
XAYO/YOYO. | 10 | 1(10%) | 3(30%) | 3(30%) | 3(30%) | 0.830 |
Promoter genotypes | ||||||
-550HH | 1 | 0(0%) | 0(0%) | 1(100%) | 0(0%) | |
-550HL | 33 | 8(24%) | 7(21%) | 11(33%) | 17(21%) | |
-550LL | 250 | 36(14%) | 90(36%) | 87(35%) | 37(15%) | 0.384 |
-550HY | 27 | 8(30%) | 5(19%) | 8(30%) | 6(22%) | |
-221LY | 250 | 35(14%) | 89(36%) | 89(36%) | 37(15%) | |
-221LX | 7 | 1(14%) | 3(43%) | 2(29%) | 1(14%) | 0.295 |
-221YY | 187 | 32(17%) | 59(32%) | 64(34%) | 32(17%) | |
-221XY | 89 | 11(12%) | 34(38%) | 33(37%) | 11(12%) | |
-221XX | 8 | 1(13%) | 4(50%) | 2(25%) | 1(13%) | 0.729 |
-550HY | 34 | 8(24%) | 7(21%) | 12(35%) | 7(21%) | |
-221LY*LX | 250 | 36(14%) | 90(36%) | 87(35%) | 37(15%) | 0.227 |
+4PP | 59 | 7(12%) | 20(34%) | 23(39%) | 9(15%) | |
+4QQ | 67 | 7(10%) | 26(39%) | 24(36%) | 10(15%) | |
+4PQ | 158 | 30(19%) | 51(32%) | 52(33%) | 25(16%) | 0.685 |
This analysis was done using the Chi Square or Fisher’s exact tests, n = 284