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. 2015 Apr 1;10(4):e0121099. doi: 10.1371/journal.pone.0121099

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© 2015 Tietjen et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Fig 5 — In all experiments, data are normalized to the replication rate of each HIV-1 strain plus 0.1% DMSO at Day 4. A-B, effects of ixoratannin A-2 (A) and boldine (B) on HIV-1_NL4-3 and HIV-1_Δvpu replication. C-D, effects of ixoratannin A-2 (C) and boldine (D) on replication of ARV-resistant HIV-1 strains.*, p < 0.008 vs. HIV-1_NL4-3 at the same concentration of ixoratannin A-2 or boldine. ǂ, p < 0.008 for strain HIV-1_PR+RT and HIV-1_INT vs. HIV-1_NL4-3 at same concentration of ixoratannin A-2.