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. 2015 Apr 1;10(4):e0121099. doi: 10.1371/journal.pone.0121099

Table 2. Properties of HIV-1 strains lacking Vpu or encoding mutations that underlie resistance to ARVs.

HIV-1 strain Protein Primary mutation(s) Resistance to ARVs tested
Δvpu vpu vpu open reading frame deleted n/a
PR+RT protease M46L, I54V, I84V, L90M IND + EFV
reverse transcriptase K101E, Y181C, G190A
RT reverse transcriptase K103N, V108I, M230L EFV
INT integrase N155H RAL