Fig 3. Cynomolgus macaque skin T cells predominantly express Vγ10Vδ1 TCR.

A. Genomic organization of cynomolgus macaque TCR Vγ and Vδ loci. Green and yellow boxes indicate functional and non-functional gene segments, respectively. Numbers given in roman numerals over the blankets indicate the subgroups of Vγ gene segments defined by Huck et al. [27]. GenBank accession numbers for the macaque genomic sequences subjected to analysis were NC_022274 for the Vγ locus and NC_022278 for the Vδ locus. kbp, kilobase pairs. Arrows indicate orientation of transcription. B. Expression of cynomolgus macaque TCR Vγ and Vδ gene segments in representative tissues. Reverse transcription PCR was conducted using a set of primer pairs specific for each TCR Vγ or Vδ gene segment shown in Table 1.