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. 2015 Apr 1;10(4):e0119448. doi: 10.1371/journal.pone.0119448

Table 15. Top important rules w.r.t. their existing KEGG pathways/GO:BPs/GO:CCs/GO:MFs in Dataset 3.

Rule #Pathway Pathways
{IL20RA+, CCR1+ ⇒ class = tumor} 1 hsa04060:Cytokine-cytokine receptor interaction
Rule #GO:BP GO:BPs
{CYBA+, C4BPA- ⇒ class = tumor} 5 GO:0006952 defense response, GO:0006954 inflammatory response, GO:0009611 response to wounding, GO:0006955 immune response, GO:0045087 innate immune response
{LYST+, BNIP3+ ⇒ class = tumor} 4 GO:0006952 defense response, GO:0009615 response to virus, GO:0006955 immune response, GO:0002252 immune effector process
{CFHR5-, REG3A- ⇒ class = tumor} 4 GO:0006952 defense response, GO:0006954 inflammatory response, GO:0009611 response to wounding, GO:0002526 acute inflammatory response
{CCR1+, CFHR5- ⇒ class = tumor} 4 GO:0006952 defense response, GO:0006954 inflammatory response, GO:0009611 response to wounding, GO:0006955 immune response
Rule #GO:CC GO:CCs
{MST1R+, TNFSF12/TNFSF13+ ⇒ class = tumor} 4 GO:0031226 intrinsic to plasma membrane, GO:0005886 plasma membrane, GO:0005887 integral to plasma membrane, GO:0044459 plasma membrane part
{MST1R+, CCR1+, TNFSF12/TNFSF13+ ⇒ class = tumor} 4 GO:0031226 intrinsic to plasma membrane, GO:0005886 plasma membrane, GO:0005887 integral to plasma membrane, GO:0044459 plasma membrane part
{LHCGR+, SLMAP+ ⇒ class = tumor} 4 GO:0031226 intrinsic to plasma membrane, GO:0005886 plasma membrane, GO:0005887 integral to plasma membrane, GO:0044459 plasma membrane part
{CYBA+, MST1R+ ⇒ class = tumor} 4 GO:0031226 intrinsic to plasma membrane, GO:0005886 plasma membrane, GO:0005887 integral to plasma membrane, GO:0044459 plasma membrane part
{TRPM2-, SMPD2- ⇒ class = tumor} 4 GO:0031226 intrinsic to plasma membrane, GO:0005886 plasma membrane, GO:0005887 integral to plasma membrane, GO:0044459 plasma membrane part
{SCN4B+, TRPM2- ⇒ class = tumor} 4 GO:0031226 intrinsic to plasma membrane, GO:0005886 plasma membrane, GO:0005887 integral to plasma membrane, GO:0044459 plasma membrane part
{MST1R+, CALCRL+ ⇒ class = tumor} 4 GO:0031226 intrinsic to plasma membrane, GO:0005886 plasma membrane, GO:0005887 integral to plasma membrane, GO:0044459 plasma membrane part
{S100A16+, MTNR1A-, NODAL- ⇒ class = normal} 4 GO:0031226 intrinsic to plasma membrane, GO:0005886 plasma membrane, GO:0005887 integral to plasma membrane, GO:0044459 plasma membrane part
{TRPM2-, SMPD2-, UGT1A10-⇒ class = tumor} 4 GO:0031226 intrinsic to plasma membrane, GO:0005886 plasma membrane, GO:0005887 integral to plasma membrane, GO:0044459 plasma membrane part
{SLMAP+, CCR1+ ⇒ class = tumor} 4 GO:0031226 intrinsic to plasma membrane, GO:0005886 plasma membrane, GO:0005887 integral to plasma membrane, GO:0044459 plasma membrane part
Rule #GO:MF GO:MFs
{BSG+, CLEC4M- ⇒ class = tumor} 2 GO:0005529 sugar binding, GO:0030246 carbohydrate binding