Table 6. Effect of voluntary running on ceramide content in tissues.
| ANOVA results | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Ceramide (pmol/mg tissue) | CD | CD + VR | P | HSD | HSD + VR | P | P VR | P HSD | P VR*HSD |
| Liver | |||||||||
| C14-Cer | 0.301 ± 0.058 | 0.221 ± 0.35 | NS | 0.231 ± 0.049 | 0.242 ± 0.05 | NS | NS | NS | NS |
| C16-Cer | 6.802 ± 0.904 | 7.233 ± 1.818 | NS | 4.031 ± 0.420 | 5.222 ± 0.811 | NS | NS | NS | NS |
| C18:1-Cer | 0.022 ± 0.003 | 0.018 ± 0.003 | NS | 0.034 ± 0.002 | 0.024 ± 0.004 | 0.05 | 0.05 | 0.01 | NS |
| C18-Cer | 0.449 ± 0.088 | 0.351 ± 0.082 | NS | 0.457 ± 0.07 | 0.4 ± 0.025 | NS | NS | NS | NS |
| C20-Cer | 0.083 ± 0.008 | 0.053 ± 0.01 | 0.05 | 0.125 ± 0.02 | 0.067 ± 0.01 | 0.05 | 0.01 | 0.05 | NS |
| C22-Cer | 0.868 ± 0.07 | 0.813 ± 0.265 | NS | 1.099 ± 0.065 | 0.786 ± 0.227 | NS | NS | NS | NS |
| C24:1-Cer | 3.013 ± 0.327 | 2.571 ± 0.376 | NS | 3.184 ± 0.103 | 3.242 ± 0.632 | NS | NS | NS | NS |
| C24-Cer | 6.284 ± 0.235 | 10.7 ± 3.8 | NS | 11.29 ± 1.19 | 7.72±2.13 | NS | NS | NS | NS |
| Total | 17.82 ± 1.29 | 21.928 ± 3.76 | NS | 20.46 ± 1.7 | 17.7 ± 3 | NS | NS | NS | NS |
| Heart | |||||||||
| C14-Cer | 0.189 ± 0.03 | 0.109 ± 0.006 | 0.05 | 0.245 ± 0.023 | 0.187 ± 0.028 | NS | 0.02 | 0.02 | NS |
| C16-Cer | 4.81 ± 1.02 | 5.1 ± 0.126 | NS | 5.63 ± 0.77 | 5.924 ± 0.926 | NS | NS | NS | NS |
| C18:1-Cer | 0.018 ± 0.002 | 0.018 ± 0.002 | NS | 0.033 ± 0.001 | 0.029 ± 0.004 | NS | NS | 0.01 | NS |
| C18-Cer | 2.110 ± 0.134 | 1.962 ± 0.263 | NS | 1.937 ± 0.376 | 2.058 ± 0.388 | NS | NS | NS | NS |
| C20-Cer | 1.334 ± 0.045 | 1.421 ± 0.050 | NS | 1.738 ± 0.296 | 1.648 ± 0.147 | NS | NS | NS | NS |
| C22-Cer | 1.609 ± 0.147 | 1.878 ± 0.052 | NS | 1.995 ± 0.284 | 1.665 ± 0.136 | NS | NS | NS | NS |
| C24:1-Cer | 1.119 ± 0.079 | 1.08 ± 0.064 | NS | 1.995 ± 0.218 | 1.636 ± 0.148 | NS | NS | 0.01 | NS |
| C24-Cer | 8.92 ± 0.6 | 10.06 ± 1.011 | NS | 10.9 ± 1.2 | 8.67 ± 0.718 | NS | NS | NS | NS |
| Total | 20.1 ± 0.78 | 21.64 ± 1.04 | NS | 24.49 ± 1.68 | 21.82 ± 1.6 | NS | NS | NS | NS |
| Soleus | |||||||||
| C14-Cer | 0.193 ± 0.012 | 0.137 ± 0.01 | 0.02 | 0.230 ± 0.01 | 0.258 ± 0.17 | NS | NS | 0.01 | 0.01 |
| C16-Cer | 4.672 ± 0.147 | 5.847 ± 0.691 | NS | 6.539 ± 0.185 | 6.530 ± 1.131 | NS | NS | 0.04 | NS |
| C18:1-Cer | 0.041 ± 0.002 | 0.041 ± 0.002 | NS | 0.049 ± 0.006 | 0.051 ± 0.003 | NS | NS | 0.02 | NS |
| C18-Cer | 3.387 ± 0.523 | 4.119 ± 0.598 | NS | 3.394 ± 0.968 | 4.649 ± 1.693 | NS | NS | NS | NS |
| C20-Cer | 0.535 ± 0.07 | 0.684 ± 0.009 | NS | 0.654 ± 0.093 | 0.827 ± 0.098 | NS | 0.05 | NS | NS |
| C22-Cer | 0.344 ± 0.021 | 0.425 ± 0.031 | NS | 0.389 ± 0.034 | 0.439 ± 0.044 | NS | NS | NS | NS |
| C24:1-Cer | 0.610 ± 0.032 | 0.707 ± 0.051 | NS | 0.765 ± 0.077 | 0.910 ± 0.065 | NS | NS | 0.01 | NS |
| C24-Cer | 2.61 ± 0.19 | 2.71 ± 0.22 | NS | 3.34 ± 0.46 | 4.13 ± 0.024 | NS | NS | 0.01 | NS |
| Total | 12.39 ± 0.83 | 14.63 ± 0.82 | NS | 15.36 ± 1.3 | 17.79 ± 2.74 | NS | NS | NS | NS |
The data are expressed as mean ± SEM; n = 4, running intensity = 5–8 km/day. Abbreviations: ANOVA, Two-way analysis of variance; CD, control diet; HSD, high-sucrose diet; VR, voluntary running.