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. Author manuscript; available in PMC: 2015 Apr 1.
Published in final edited form as: Nephron Exp Nephrol. 2014 Nov 19;128(0):80–88. doi: 10.1159/000368411

Fig. 6.

Fig. 6

wmISH of Ret gene expression in wild-type and Wnt5a knockout mouse embryos. a, d At E11.5, the UB forms at the metanephric region and starts to branch in the wild-type embryo. b, e In some Wnt5a knockout embryos, the regions containing Ret-expressing IM are limited, the site of UB outgrowth occurred at the medial region and the branching is delayed. c, f In other Wnt5a knockout embryos, there are additional UB outgrowth sites. At E15.5, some Wnt5a knockout embryos developed unilateral kidney hypogenesis (i), while others have duplex kidneys/ureter (j).