Extended Data Table 1.
Descriptive characteristics of meta-analyses
| Meta-analysis | Total number of studies |
Maximum number of subjects |
Number of SNPs* |
λ GC |
|---|---|---|---|---|
| European sex-combined | ||||
| GWAS | 80 | 234,069 | 2,550,021 | 1.526 |
| Metabochip | 34 | 88,137 | 156,997 | 1.25 |
| Joint GWAS+Metabochip | 114 | 322,154 | 2,554,623 | 1.084 |
| European men | ||||
| GWAS | 72 | 104,666 | 2,473,152 | 1.279 |
| Metabochip | 34 | 48,274 | 152,326 | 1.121 |
| Joint GWAS+Metabochip | 106 | 152,893 | 2,477,617 | 1.006 |
| European women | ||||
| GWAS | 74 | 132,115 | 2,491,697 | 1.336 |
| Metabochip | 33 | 39,864 | 153,086 | 1.029 |
| Joint GWAS+Metabochip | 107 | 171,977 | 2,494,571 | 1.002 |
| European population-based | ||||
| GWAS | 49 | 162,262 | 2,502,573 | 1.385 |
| Metabochip | 20 | 46,263 | 155,617 | 1.034 |
| Joint GWAS+Metabochip | 69 | 209,521 | 2,506,448 | 1.003 |
| All ancestries | ||||
| GWAS | 82 | 236,231 | 2,550,614 | 1.451 |
| Metabochip | 43 | 103,047 | 181,718 | 1.25 |
| Joint GWAS+Metabochip | 125 | 339,224 | 2,555,496 | 1.004 |
*
For the GWAS and joint GWAS+Metabochip analyses, SNP count reflects n ≥ 50,000.