Figure 4. Pedigree of a family with a patient with MM and HSP90-SUMO1 as the paratarg.

Shown is the pedigree of the family and a Western blot for the HSP90 state. Sumoylated HSP90 was detected in the female patient having MM and in her healthy sister. Each of the 2 sisters had 2 children, one of whom was a carrier of HSP90-SUMO1, while the other was not. All children were healthy.