Skip to main content
. 2014 Dec 1;125(1):194–207. doi: 10.1172/JCI76012

Figure 1. Teffs, but not Tregs, upregulate glycolytic metabolism during inflammatory processes in vivo.

Figure 1

(A–C) EAE was induced in 2D2 TCR transgenic mice, and RNA was extracted from spinal cords of mice with active disease or in vitro MOG-stimulated (MOG stim) 2D2 T cells as indicated (A) for real-time PCR of (B) inflammatory and (C) metabolic gene expression. (D) EAE was induced in wild-type mice and CD4+ T cells in spleens, and inguinal lymph nodes of mice with active disease were examined using flow cytometry. Data are representative of 2 experiments (A–C, n = 10; D, n = 5) and shown as mean ± SD. *P < 0.05.