Table 3. Cystometric parameters of Control, CYP, CYP+ RAPA and CYP+CQ treated rats.
Urodynamic Parameters | Control | CYP | CYP+RAPA | CYP+CQ |
---|---|---|---|---|
Basal pressure (cm H 2 O) | 10.00±1.37 | 13.60±2.75 | 11.30±2.44 | 14.50±1.97 a |
Threshold pressure (cm H 2 O) | 42.10±3.36 | 36.70±2.33 | 37.50±2.50 | 38.80±3.40 |
Maximum pressure (cm H 2 O) | 52.90±3.29 | 51.10±5.57 | 50.90±5.27 | 50.90±3.86 |
Micturition frequency (No/h) | 7.60±1.14 | 19.20±2.59 a | 9.60±1.14 b | 28.60±2.61 a b |
Intercontraction interval (mins) | 7.95±1.35 | 3.17±0.42 a | 6.43±0.66 b | 2.11±0.20 a b |
Bladder capacity | 1.07±0.17 | 0.42±0.06 a | 0.89±0.07 b | 0.28±0.036 a b |
Data presented as means ± SD (n = 5).
a indicates a significant difference compared to the corresponding control group value (P <0.05).
b indicates a significant difference compared to the corresponding CYP group value (P <0.05).