Skip to main content
. Author manuscript; available in PMC: 2015 Apr 2.
Published in final edited form as: Cell Rep. 2015 Mar 26;10(12):1967–1973. doi: 10.1016/j.celrep.2015.02.061

Figure 2. MT release rates of head- and NL-pulled kinesins under different nucleotide conditions.

Figure 2

(A) Without nucleotide, monomers release in response to external force (left). k1 (middle) and k2 (right) of kinesin monomers pulled from the head and NL increase with force in both forward (positive forces) and backward directions. (B) With 1 mM ATP in solution, kinesin can release by force or hydrolysis of the bound nucleotide (left). MT release rates of the headand NL-pulled kinesins increase compared to the apo condition. (C) At 1 mM ADP, kinesin can release from MTs by force or ADP binding (left). NL-pulled kinesins show slower release under backward forces. Error bars represent 95% confidence intervals.

See also Figures S3 and S4.