Figure 8. Exosomes regulate PTEN, BIM, p-ERK and p-Akt signaling in CM. A, TargetScan shows the 3’ UTR of PTEN and BIM (BCL2L11) containing the conserved miR-19a binding site. B, Western blotting analyses of PTEN and BIM, and corresponding semi-quantitative data in CM. C, Western blotting analyses of p-ERK and p-Akt, and corresponding semi-quantitative data in CM. *, p<0.05 vs medium control, and #, p<0.05 vs ExoNull treated, respectively.