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. Author manuscript; available in PMC: 2015 Oct 1.
Published in final edited form as: Kidney Int. 2014 Oct 22;87(4):719–727. doi: 10.1038/ki.2014.343

Figure 1.

Figure 1

Systemic, cardiac, and renal characteristics in Sham, hypertension (HT), coronary artery stenosis (CAS), and CAS+HT pigs. A. Circulating PGF2-α isoprostane. B. Systemic transforming growth-factor (TGF)-β1. C-D. Representative cardiac CT images obtained at the middle left-ventricle (LV). In hypertensive animals (HT and CAS+HT), the LV wall is thickened. The arrow in C shows myocardial lateral wall thinning distal to a high-grade CAS (illustrated in D). E, Cardiac output. F, Myocardial perfusion. G, LV muscle mass (LVMM). H, Glomerular filtration rate (GFR). I, Change in renal blood flow (ΔRBF) in response to acetylcholine (Ach). J, Intratubular concentration (ITC) in the different nephron segments. *P<0.05 vs. Sham; #P<0.05 vs. HT; &P<0.05 vs. CAS.