Table 3.

Adjusted Hazard Ratios (95% Confidence Intervals) for Incident CKD by Serum Magnesium Levels

Serum magnesium	Quartile 1a	Quartile 1b	Quartile 2	Quartile 3	Quartile 4	P-trend
mmol/L	0.25–0.70	0.75	0.80	0.85	0.90–1.15
Model 1	2.14 (1.83, 2.50)	1.71 (1.48, 1.98)	1.17 (1.02, 1.35)	1.13 (0.98, 1.30)	1.00	<0.001
Model 2	1.75 (1.49, 2.06)	1.58 (1.36, 1.83)	1.13 (0.98, 1.30)	1.14 (0.99, 1.31)	1.00	<0.001
Model 3	1.58 (1.35, 1.87)	1.47 (1.27, 1.71)	1.06 (0.93, 1.22)	1.09 (0.95, 1.26)	1.00	<0.001

Model 1: controlling for race-center, age, and gender

Model 2: Model 1 + baseline eGFR, diabetes, and hypertension medication status

Model 3: Model 2 + education levels, household income, health insurance status, systolic blood pressure, prevalent coronary heart disease, smoking status, log-transformed triglycerides, HDL-C, log-transformed LDL-C, and serum albumin.

P-values for trend were obtained by coding serum magnesium levels as a continuous variable from 0 to 4.