Table 2.

Diagnostic and clinical instruments and endophenotype measures in COGS-1 and COGS-2.

COGS-1	COGS-2
Day 1–clinical assessment	Day 1–clinical assessment
Probands, Relatives, HCS	Patients	HCS
DIGS (including SANS/SAPS)	SCID I/P w/additional items from DIGS	SCID I/NP w/additional items from DIGS
FIGS	FIGS and pedigree analysis	FIGS and pedigree analysis
BPRS	MMSE	MMSE
GAF	GAF	GAF
Day 2–endophenotype assessment		SANS/SAPS-modified version from the DIGS
Test order A	Test order B	SOF
P50	CVLT	RFS
AS	DS-CPT	UPSA-B
PPI	LNS	Day 2–endophenotype assessment
Break	CPT-IP	PPI
SANS/SAPS	PENN CNB	AS
PENN CNB	SANS/SAPS	CPT-IP
CPT-IP	Break	CPT-DS
LNS	PPI	LNS
CVLT	AS	CVLT
DS-CPT	P50	PENN CNB
		Event-related potentials: mismatch negativity (MMN), P300

Abbreviations:

DIGS: Diagnostic Interview for Genetics Studies

FIGS: Family Interview for Genetic Studies.

BPRS: Brief Psychiatric Rating Scale–Expanded, Anxiety Scale

MMSE: Mini-Mental State Exam

GAF: Global Assessment of Functioning Scale

SANS: Scale for the Assessment of Negative Symptoms.

SAPS: Scale for the Assessment of Positive Symptoms.

SOF: Scale of Functioning

RFS: Role Functioning Scale

UPSA-B: UCSD Performance-based Skills Assessment–Brief

AS: Antisaccade measurements

P50: P50 event-related potentials suppression

PENN CNB: U. Pennsylvania Computerized Neurocognitive Battery

LNS Letter-number span test.

CVLT California Verbal Learning Test, Version II

CPT: Continuous performance task (DS = degraded stimulus version; IP = identical pairs version)