Table 2. Outcomes in T-Cell Depleted and Unmodified Grafts.
| Outcome | TCD (95% CI) : N=52 | Unmodified (95% CI) : N=115 | p-value |
|---|---|---|---|
| Relapse-free survival | 0.653 | ||
| 1 year | 55.8 (41.3-68.0) | 56.3 (46.7-64.8) | |
| 3 year | 42.8 (28.8-56.1) | 35.9 (26.8-45.0) | |
|
| |||
| Overall survival | 0.854 | ||
| 1 year | 63.5 (48.9-74.9) | 62.4 (52.8-70.5) | |
| 3 year | 42.6 (28.6-56.0) | 43.0 (33.3-52.4) | |
|
| |||
| Relapse incidence | 0.107 | ||
| 1 year | 19.2 (9.8,31.0) | 20.1 (13.3-27.9) | |
| 3 year | 21.3 (11.3,33.4) | 35.5 (26.5-44.6) | |
|
| |||
| Non-relapse mortality | 0.368 | ||
| 100 day | 15.4 (7.1-26.5) | 9.6 (5.1-15.8) | |
| 1 year | 25.0 (14.2-37.4) | 23.6 (16.3-31.8) | |
| 3 year | 35.9 (22.6-49.4) | 28.6 (20.5-37.3) | |
|
| |||
| Acute GVHD (grade 2-4) | 0.001 | ||
| 100 day | 17.3 (8.5-28.8) | 42.6 (33.4-51.5) | |
|
| |||
| Acute GVHD (grade 3-4) | 0.164 | ||
| 100 day | 7.7 (2.4,17.0) | 15.7 (9.7,22.9) | |
|
| |||
| Chronic GVHD | 0.006 | ||
| 3 year | 13.5 (5.8-24.3) | 33.4 (24.9-42.2) | |