Table 3. Univariate Analyses of risk factors associated with relapse-free survival (RFS) and overall survival (OS).
RFS, HR (95% CI) | p-value | OS, HR (95% CI) | p-value | |
---|---|---|---|---|
Age | 0.005 | 0.003 | ||
≤ 50 years | reference | Reference | ||
> 50 years | 1.946 (1.228,3.085) | 2.084 (1.290,3.366) | ||
| ||||
Gender | 0.747 | 0.775 | ||
Male | reference | Reference | ||
Female | 0.937 (0.628,1.396) | 0.942 (0.623,1.423) | ||
| ||||
Immunophenotype | 0.179 | 0.280 | ||
T-Cell | reference | Reference | ||
B-Cell | 1.349 (0.701,2.596) | 1.212 (0.628,2.339) | ||
Other | 0.505 (0.139,1.834) | 0.495 (0.136,1.800) | ||
| ||||
Cytogenetic Risk | 0.191 | 0.568 | ||
Good or Standard | reference | Reference | ||
Poor | 1.325 (0.869,2.022) | 1.134 (0.737,1.745) | ||
| ||||
Status at HSCT | 0.029 | 0.034 | ||
CR1 | reference | Reference | ||
CR2 | 1.547 (1.047,2.287) | 1.546 (1.033,2.313) | ||
| ||||
Donor type | 0.768 | 0.630 | ||
Matched related | reference | Reference | ||
Matched unrelated | 0.899 (0.585,1.381) | 0.967 (0.622,1.503) | ||
Mismatch | 1.144 (0.600,2.183) | 1.339 (0.698,2.567) | ||
| ||||
Stem Cell Source | 0.381 | 0.387 | ||
Bone marrow | reference | Reference | ||
Peripheral blood | 1.224 (0.778,1.925) | 1.228 (0.771,1.956) | ||
| ||||
Graft type | 0.654 | 0.853 | ||
Unmodified | reference | Reference | ||
TCD | 0.906 (0.589,1.395) | 1.042 (0.673,1.613) | ||
| ||||
TBI | ||||
no | reference | 0.281 | reference | 0.725 |
yes | 0.800 (0.533,1.201) | 0.926 (0.603,1.423) |