Table 2.
Multivariable Associations between Vascular Health Measures and Walking Speed (m/s)
| cIMT (mm) | cAD (mm) | Carotid plaque burden | ||||||
|---|---|---|---|---|---|---|---|---|
|
| ||||||||
| β (SE) | P value | β (SE) | P value | OR (95% CI) None vs. minimal |
P value | OR (95% CI) None vs. high |
P value | |
|
| ||||||||
| Unadjusted | −0.080 (0.012) | <.001 | −0.497 (0.066) | <.001 | 1.140 (0.669, 1.943) | 0.6 | 0.625 (0.384, 1.018) | 0.06 |
| Model 1 | −0.045 (0.014) | 0.001 | −0.427 (0.076) | <.001 | 1.030 (0.529, 2.005) | 0.9 | 0.339 (0.182, 0.631) | 0.001 |
| Model 2 | −0.017 (0.015) | 0.3 | −0.189 (0.081) | 0.02 | 1.201 (0.583, 2.477) | 0.6 | 0.423 (0.213, 0.839) | 0.01 |
| Model 3 | −0.016 (0.015) | 0.3 | −0.176 (0.085) | 0.04 | 1.346 (0.635, 2.852) | 0.4 | 0.569 (0.277, 1.169) | 0.1 |
LDL-C: low density lipoprotein cholesterol, HDL-C: high density lipoprotein cholesterol, cIMT: carotid intima-media thickness, cAD: carotid adventitial diameter
Model 1 : Adjusted for age, race, site, menopausal status, SBP.
Model 2 : Model 1 + BMI.
Model 3 : Model 2 + LDL-C, HDL-C, log transformed triglycerides, log transformed HOMA index, smoking status, ever use of cardiovascular medications (antihypertensive/lipid lowering/heart medication), ever use hormone therapy, diabetes status, and physical activity.