Table 2.
Whole brain functional MRI (fMRI) results comparing BOLD response in the alcohol-exposed (AE) group relative to the control (CON) group during the Stop-signal task (cluster level α < .05, with voxel level α < .001).
| Stop-signal contrast | Anatomical region | t (1, 41) | Effect size | Brodmann area | Volume (μl) | Talairach coordinates (reported in LPI)
|
||
|---|---|---|---|---|---|---|---|---|
| X | Y | Z | ||||||
| Baseline (motor responding) | R precentral gyrus | 4.65 | .351 | 6 | 1408 | 48.9 | −2.8 | 31.8 |
| L pre- and postcentral gyrus | 4.75 | .361 | 6, 4 | 1408 | −45.1 | −11.0 | 32.0 | |
| All-stop | L postcentral gyrus | 4.63 | .349 | 4 | 2304 | −47.0 | −13.0 | 34.8 |
| R precentral gyrus | 4.51 | .337 | 6 | 1344 | 48.7 | −6.9 | 35.0 | |
| L putamen/lentiform nucleus | 4.31 | .317 | – | 1088 | −27.9 | −7.1 | −.9 | |
| L SMA/middle cingulate | 3.62 | .232 | 6, 24 | 1088 | −7.2 | −.5 | 49.2 | |
| R middle cingulate | 4.26 | .312 | 24 | 896 | 12.0 | −13.9 | 38.6 | |
| Medium | L insula/superior temporal gyrus | 5.11 | .395 | 38 | 1024 | −35.5 | −2.0 | −8.5 |
| R middle/medial temporal gyrus | 5.35 | .417 | 21, 20 | 960 | 50.0 | 2.7 | −22.9 | |
| Hard | L postcentral gyrus | 4.85 | .371 | 3, 4 | 5312 | −41.9 | −19.3 | 43.6 |
| R pre- and postcentral/supramarginal gyrus | 5.13 | .397 | 6, 40 | 3712 | 53.0 | −15.8 | 29.9 | |
| L middle cingulate/SMA | 4.063 | .292 | 24, 6 | 2688 | −8.3 | −2.0 | 45.0 | |
| L precentral gyrus | 4.40 | .326 | 6 | 1024 | −25.5 | −4.5 | 29.8 | |
| L thalamus/caudate | 3.84 | .269 | – | 960 | −13.7 | −9.0 | 14.7 | |
| L middle/anterior cingulate | 4.51 | .337 | 24 | 960 | .4 | −2.1 | 32.3 | |
| Hard–easy | R SMA/superior frontal gyrus | 4.18 | .304 | 6 | 1344 | 10.0 | 19.0 | 56.0 |
| SMA/medial/superior frontal gyrus | 4.17 | .303 | 6, 24, 32 | 1088 | −2.0 | 7.0 | 44.0 | |
| Cuneus | 3.62 | .247 | 18 | 1024 | 6.0 | −81.0 | 12.0 | |