Table 3.

Significant single-sample t-test results for the alcohol-exposed (AE) and control (CON) groups (cluster level α < .025, with voxel level α < .001) on the stop-Signal functional MRI (fMRI) task.

Stop-signal contrast	Anatomical region	Brodmann area	Volume (μl)	Talairach coordinates (reported in LPI)
				X	Y	Z
The CON group
Baseline (motor responding)	L pre/postcentral gyrus	4, 3	6656	−43.3	−17.6	43.5
	L lingual gyrus/cuneusa	17, 18	5632	−3.8	−86.5	−1.2
	SMA	6	2304	−1.6	−.9	53.2
	L superior/middle temporal gyrus	22	2240	−55.0	−14.7	9.0
	L putamen	–	1664	−24.9	−6.8	10.6
	R superior temporal/supramarginal gyrus	40	1408	58.2	−33.7	18.5
	R superior temporal gyrus	22	1216	50.8	−13.0	4.2
	R precentral gyrus	6	1152	48.7	−4.1	34.0
All-stop	L pre/postcentral gyrusa	4	8896	45.4	−15.9	39.3
	R pre/postcentral gyrusa	6, 4	3648	47.7	−10.0	36.1
	L putamena	–	2688	−31.2	−18.0	9.0
	R angular/inferior parietal gyrus	40	2432	34.1	−55.7	42.0
	R middle temporal gyrus	21	1088	50.7	−34.9	−2.1
	L cuneus/middle occipital gyrusa	18	1088	−22.5	−84.1	16.2
	Insulaa	13	960	−43.9	−10.1	12.5
Easy	L postcentral gyrusa	4	6336	−48.2	−13.8	34.3
	L posterior cingulate/precuneusa	31	4672	−8.0	−56.2	17.6
	R inferior parietal lobule	40	3264	37.2	−49.1	41.5
	R middle cingulate gyrus	32	3136	3.1	25.9	33.1
	R precentral gyrusa	4	3136	46.9	−11.1	40.5
	R middle temporal gyrus	22	2240	48.2	−32.9	−1.4
	R posterior cingulatea	30	1792	14.4	−52.0	9.7
	L middle/superior frontal gyrusa	8	1344	−3.3	24.1	40.0
	L paracentral lobulea	6	1280	−11.6	−24.6	59.8
	R cingulate	23	1216	.9	−24.2	27.4
	R inferior/middle frontal gyrus	9	1088	38.5	3.9	33.2
	R middle/superior frontal gyrus	10	960	31.1	47.0	14.9
	R middle frontal gyrus	9	960	38.0	34.5	28.3
	L cerebellum	–	896	−27.7	−75.0	−38.0
	L parahippocampal gyrusa	–	896	−22.3	−15.0	−11.7
	L inferior parietal lobule	7	896	−30.0	−55.9	41.4
Medium	L postcentral gyrusa	4	5248	−48.1	−13.2	38.0
	L superior gyrus/rolandic operculuma	42, 22	2432	−52.5	−8.5	9.2
	R precentral gyrusa	6	2178	45.1	−9.8	41.2
	SMAa	6	1344	−2.0	−4.8	53.7
	L putamena	–	960	−26.3	−10.1	3.5
	R superior temporal gyrus/rolandic operculuma	22, 43	960	52.7	−9.5	9.3
Hard	L pre/postcentral gyrusa	6, 1, 4a	3200	−42.9	−16.7	46.1
	L cuneus/middle occipital gyrusa	18	1792	−20.3	−84.1	17.3
	L cuneus/calcarine gyrusa	18, 31	1152	−3.6	−68.6	18.2
	R cuneus/calcarine gyrusa	31	896	19.1	−62.4	18.9
	R angular gyrus	39, 7	896	36.9	−62.7	38.9
Hard–easy	R cingulatea	32, 6	6464	3.0	22.1	36.3
	R insula/inferior frontal gyrusa	13	3456	39.0	19.1	10.1
	R middle/superior frontal gyrusa	10	2495	30.1	47.0	17.1
	Cerebellar vermisa	–	1472	.8	−51.4	−22.3
The AE group
Baseline	Middle cingulatea	31	3392	3.4	−30.3	36.8
	R superior frontal gyrusa	8	896	15.7	27.0	37.7
All-stop	R thalamus	–	896	14.0	−5.0	8.0
Medium	R inferior frontal gyrus	45	896	46.3	23.3	6.3
Hard	R middle/superior temporal gyrus	22	1984	49.9	−40.9	10.1
	R thalamus	–	1024	17.5	−10.5	14.8
	R inferior parietal/supramarginal gyrus	40	896	56.0	−28.7	24.9
Hard–easy	Paracentral lobule	6, 5	1216	.3	−29.4	53.5
	L precuneus/postcentral gyrus	7	1024	−15.0	−42.0	63.2
	L postcentral gyrus	2, 3	960	−47.6	−21.3	41.3

^aIndicates negative BOLD response.